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A completely new study shows that the compound conolidine, present in the pinwheel flower, only binds to one unique scavenger receptor."We confirmed that conolidine binds for the newly discovered opioid receptor ACKR3, even though displaying no affinity for the other four classical opioid receptors. By doing this, conolidine blocks ACKR3 and preven
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The atypical chemokine receptor ACKR3 has just lately been noted to work as an opioid scavenger with unique unfavorable regulatory properties to various families of opioid peptides.Vegetation are historically a supply of analgesic alkaloids, although their pharmacological characterization is usually constrained. Amongst these types of natural analg
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